gabaa receptor δ subunit (n-k8凯发

immunogen: fusion protein from the n-terminal region of the δ subunit of rat gabaa receptor • host: rabbit • species reactivity: ( ) mouse and rat • applications: icc, ihc, and wb • gabaa-rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. it is a multimeric subunit complex with six α's, four b’s, and four g’s, plus alternative splicing variants of some of these subunits. several studies demonstrate that the d-subunit of the receptor may affect subunit assembly and may also confer differential sensitivity to neurosteroids and to ethanol.